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The Early Dementia Blood Analysis Test of the University of Cambridge begins

The Early Dementia Blood Analysis Test of the University of Cambridge begins

Katy Prickett

BBC News, Cambridgeshire

Race against Dementia Sir Jackie Stewart and Dr. Maura Malpetti, both smiling. Sir Jackie is left and has white hair to the ear, took back his forehead and wears a white shirt. On the right, Dr. Malpetti has long and dark hair on his shoulders. She wears a blue jacket on a white top.Career against dementia

Sir Jackie Stewart’s career against the beneficial dementia organization gave Dr. Maura Malpetti a scholarship in 2021

A simple blood test designed to detect dementia decades before it is developed is being implemented throughout the United Kingdom as part of a new “very exciting” study.

Scientists from the University of Cambridge will use the approach to measure brain changes in people with dementia as an alternative to “more expensive brain scan.”

Is Based on the initial investigation directed by Dr. Maura Malpetti, who received the race against the dementia scholarship in 2021 of the charity organization founded by Sir Jackie Stewart, in association with Alzheimer’s Research UK.

The winner of the World Formula 1 championship three times described the work of Dr. Malpetti as “innovative.”

University of Cambridge a side view of Dr. Maura Malpetti, which has long and long hair and carries a white laboratory robe on a white sweater. It is sitting on the desk and turning to look towards a computer screen that has nine aligned brain scanns, all blue and purple, some with orange areas. Cambridge University

The deployment of the United Kingdom focuses on cerebral inflammation, which is high in frontotemporal dementia

“By applying the principles of precision, teamwork and inventive formula 1 to the world of medical research, we can more efficiently boost progress towards a cure for dementia,” added Sir Jackie.

He established a career against dementia after the diagnosis of frontotemporal dementia of his wife Helen.

The investigation will focus on this form of dementia, which is also The type of actor Bruce Willis was diagnosed in 2023 – But aims to help accelerate the development of treatments for other types of dementia.

Reuters a close -up of actor Bruce Willis attending the European premiere of "Glass" In London, Great Britain, on January 9, 2019. He has a bald head and is smiling widely. Simply glimpsed there is a black jacket and a white shirt. Reuters

When Bruce Willis’s family shared his diagnosis, they said there were no treatments for the disease, which they expected would change

Dr. Malpetti, associate of senior research in the Department of Clinical Neurosciences of the University, found that molecular changes associated with cerebral inflammation and dementia can also be detected in the blood, decades before the symptoms of physical dementia.

In general, they are only collected by “more expensive brain scans,” said the university.

Cerebral scanning also takes longer to carry out and require specialized equipment that is not available in all parts of the country.

Dr. Malpetti described the new essay as “very exciting program”, saying: “We are focusing on the changes in the brain that can manifest from 10 to 20 years before the symptoms, with the hope that in the future we can treat them Early enough to stop the disease before symptoms occur. “

University of Cambridge Dr. Maura Malpetti with two other women, who are part of The Open Network for the Frontotemporal Dementia Inflammation Team (in fire). She is on the right with long and dark hair on a dark jacket and a pink sweater. On her right there is a woman with long and blond hair on a pale blue sweater and her right is a woman with curly brown hair and a gray upper part. Behind them there are shelves full in a laboratory environment. Cambridge University

The open network for the investigation of the Frontotemporal dementia inflammation team (in fire) began in Cambridge

Dementia mainly affects people over 65, but frontotemporal dementia tends to begin a younger age, although it can also affect older people.

There are about 20,000 people in the United Kingdom who live with frontotemporal dementia, but Dr. Malpetti said that because it is less common, people with the condition are often diagnosed erroneously.

The research has already shown that greater cerebral inflammation is associated with a faster clinical decrease in people with frontotemporal dementia, similar to Alzheimer’s disease, and Dr. Malpetti said that this points to the immunotherapy potential in the treatment of dementia .

Dr. Richard Oakley, associate director of research and innovation in Alzheimer’s society, said: “This is another exciting step to revolutionize how we could diagnose diseases that cause dementia in an early and precise way.

“A simple blood test could offer a faster and faster diagnostic method, helping to give the most time to plan and prepare for the future.”

The study plans to recruit people from as many different areas and communities from the United Kingdom as possible.

It will be based on more than 20 research and medical care centers to help identify who could benefit more from disease -modifying treatments.

Another dementia blood test trial that currently runs in the United Kingdom includes two They are part of the challenge of blood biomarkers.

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